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Toll-like receptor signaling in severe acute respiratory syndrome coronavirus 2-induced innate immune responses and the potential application value of toll-like receptor Immunomodulators in patients with coronavirus disease 2019

19 However, tumor cells also utilize GST to form a GSHX complex between antitumor drugs and GSH, proceeding to excrete the complex out of the cell by Pgp and MRP

FIGURE 7 Next, we silenced Nrf2 and HO-1 expression using siRNA in MC3T3-E1 cells, and the silencing effect was confirmed by western blotting (Figures 7GJ)

However, increasing numbers of studies have shown that mtROS are the primary mediators of NLRP3 inflammasome activation