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They also provide drug delivery across the bloodbrain barrier (Henna and Pramod, 2020)

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We observed that RSL3 treatment significantly increased the accumulation of labile iron, ROS and lipid peroxides and accompanied by the reduction or disappearance of mitochondrial cristae in prostate cells, while GPX4 decreased

Treated animals also showed a significant reduction in the degeneration of Purkinje cells and CA1 hippocampal neurons and a reduction in the GFAP-positive cells in the corpus callosum