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Lastly, Ucn 3 mRNA and peptide expression have been identified in the amygdala, lateral septum, ventromedial hypothalamus and paraventricular nucleus of the hypothalamus, basomedial nucleus of the stria terminalis, dorsal raphe nucleus and the area postrema (Lewis et al., 2001

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They report that stress hormones activate neuronal oxidative stress, which increases the release of additional stress hormones and cause neuronal damage in the hippocampus in AD brains

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