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Analysis of gene expression data has suggested that GHK-Cu may up-regulate genes associated with repair and regeneration while down-regulating genes associated with inflammation and cellular damage

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Kulkarni K, Kelderman J, Coleman H, Aguilar M-I, Parkington H, Del Borgo M

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Thanks to the positive charge, it also creates a complex with AHAs (AHAs like to lose a hydrogen ion and be negatively charged, so the positive and the negative ions attract each other) that causes a "time-release AHA effect" and reduces the irritation associated with AHAs

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