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More importantly, as will be discussed below, because the genome content tends to be highly conserved between bona fide carriage and disease isolates, subtle differences in the ability to modulate gene expression in host microenvironments, to engage in productive cross-talk with the cells also at metabolic level, to elude the host immune defenses, and to evolve over a short period of time have been proposed as major determinants of the hyperinvasive phenotype

Enhanced Immune Function: Glutathione plays a vital role in the body's detoxification process by binding to toxins, heavy metals, and harmful substances and facilitating their elimination from the body

This disruption affects the efficiency of cellular respiration, ultimately impairing energy production (Holt and Bard, 2005

Survivin: Survivin is an anti-apoptotic protein that exerts its effect by inhibiting caspase-3