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Because the pharmacokinetics are well understood and down-stream metabolites are easily quantifiable from urine, APAP is often used as a test case for the application of metabolic profiling in contexts as diverse as epidemiology (Loo et al

Bacterial infection causes stress-induced memory dysfunction in mice

Redox dysregulation is also linked to protein misfolding by the production of aberrant, non-native disulfide bonds in both mutant SOD1 and TDP-43, which leads to the formation of inclusions and induces toxicity

Companion molecules GSSSG and lipoic acid (LASS) did not exhibit these effects, thus highlighting the unique characteristics of LASSS