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The Journal of Physical Chemistry Letters 6 , 29762986, (2015)

Medically reviewed by Oghenefejiro Okifo | MD , Harvard Medical School | Henry Ford Hospital - Detroit, MI on October 29th, 2025

Using genetic deletion of Cth , we determined that CTH can affect macrophage function via enhanced gene and protein expression through NF-B phosphorylation and suppression of DNA methylation and maintenance of mitochondrial function through redox homeostasis