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Experimental Materials All extracellular flux analysis consumables were purchased from Agilent (North Billerica, MA, USA)

1), an antiprotozoal compound synthesized in 1949 [52], exhibits antitumor activity against leukemia cell lines with a superior therapeutic index compared to ATO [53]

76 GST prodrugs appear to have a more favorable adverse-event profile, given that they are ingested as an inactive compound and undergo breakdown to release cytotoxic metabolites only in the presence of high concentrations of enzymes that occur in the proximity of tumor cells, thereby reducing collateral damage to healthy cells

Alternatively, we generated N-terminal GSH1 translation reporters to investigate where GSH1 protein is targeted