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Kelley BP, Brown SP, Warren GL, Muchmore SW

75 Strikingly, transplantation of the gut microbiota from wild-type mice to AD mice alleviates the A load, neurofibrillary tangles and glial reactivity

doi: 10.1007/s10681-016-1774-3 36 LiZ.AhammedG

Trained immunity is activated by PAMPs such as LPS or -glucan via PRR signaling, resulting changes in transcription programs through epigenetic regulation that can persist for up to several weeks (125, 126)