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These variations are concentrated in genes related to protein synthesis, mitochondrial function, and virulence factors like HSP78 and sterol 24-C-methyltransferase, along with CNVs affecting mitochondrial transport, vesicular trafficking, and protein turnover (Shaw et al., 2019

BarbarrojaNRuiz-PonceMCuesta-LopezLPerez-SanchezCLopez-PedreraCArias-de la RosaIet alNonalcoholic fatty liver disease in inflammatory arthritis: relationship with cardiovascular risk

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It was reported that metabolic activation of numerous other flavonoids was involved in or aggravated their toxicities (Table 1)