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Jacques, N., Karoutsos, S., Marais, L

The estimated mean change in body weight at week 68 was 20.4% with CagriSema versus 3.0% with placebo (a difference of about 17 percentage points), and more CagriSema participants reached weight-loss thresholds of 5%, 20%, 25%, and 30% than placebo

nevertheless, an open uncontrolled clinical trial in 17,473 postmenopausal women who participated in a one-year dietary intervention that involved decreasing fat intake and increasing intake of fruits, vegetables, and whole grains found those who lost at least 10% of their baseline body weight were more likely to experience a reduction in their menopausal symptoms than those who did not lose weight

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