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6.1 Role of ferroptosis in cancer therapy At present, the first-line chemotherapy for ovarian cancer is platinum drugs combined with paclitaxel and targeted drugs bevacizumab and PARP inhibitors are often used for maintenance therapy

a , Doseresponse curves for control (shCtrl) and Smurf1 silenced (shSmurf1) HCT116 cells treated with SMART1 for 72 h (n = 4 independent experiments)

In vitro , 5-amino-1MQ significantly reduced intracellular MNA, increased intracellular NAD + , and suppressed lipogenesis in adipocytes

[2] identified markedly different plasma immune signatures in early ME/CFS patients (less than 3-year duration) compared with healthy controls