mk571 glutathione mrp1 3β-Acetyl tormentic acid reverts MRP1/ABCC1 mediated cancer resistance through modulation of intracellular levels of GSH and inhibition of GST activity Nitrogen monoxide (NO)-mediated iron release

Nitrogen monoxide (NO) mediated iron release from cells is linked to NO induced glutathione efflux via multidrug resistance associated protein 1 PNAS MRP1 modulators synergize with buthionine sulfoximine to exploit collateral sensitivity and selectively kill MRP1 expressing cancer cells ScienceDirect Multidrug Resistance Protein 1 (MRP1, ABCC1), a Multitasking ATP binding Cassette (ABC) Transporter PMC In vitro function and in situ localization of Multidrug Resistance associated Protein (MRP)1 (ABCC1) suggest a protective role against methyl mercury induced oxidative stress in the human placenta Archives of Toxicology Springer

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