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Significant between-group differences were observed in the incidence of CIPN and a 70% reduction in risk in the omega-3 fatty acid group [136]

Intermittent claudication in peripheral arterial disease In peripheral arterial disease, atherosclerosis of the arteries that supply the lower extremities may diminish blood flow to the point that the metabolic needs of exercising muscles are not sufficiently met, thereby leading to ischemic leg or hip pain known as claudication (see the page on Intermittent Claudication in Peripheral Arterial Disease) (63)

However, more human studies are required to substantiate these claims