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Following activation, hepatic stellate cell (HSC) proliferation increases and they secrete extracellular matrix (ECM) to drive the fibrotic process

Results and discussion Characteristics and quality of the studies After excluding 80 duplications, a total of 172 potentially relevant citations were identified and screened

published two randomized controlled studies, in which no significant benefit of MLG on VA was found.142,143 MLG is recommended as an effective treatment to reduce the ME in BRVO after a period of 3 to 6 months after onset and following absorption of the majority of hemorrhage if VA is 20/40 or worse.61,62,141 If the fluorescein angiogram reveals macular nonperfusion, laser therapy is not warranted.141 Subramanian et al.65 recommended laser treatment in patients with poor VA (20/200 or worse) secondary to ME due to BRVO, before more aggressive approaches (as intravitreal TA)

Mercury-Containing Amalgam Fillings Account for Less Than 6% of Posterior Tooth Fillings in 2022