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This permanently damages the compounds structure, destroying its biological activity

According to clinical research parenteral administration (intramuscular or intravenous) is preferred over other drug administration routes in case of emergency situations as it provides first-pass metabolism avoidance, reliable therapeutic concentrations and better bioavailability of dosage (2) It can also be used in situations when oral route is not feasible

Causing throbbing head pain and accompanied by symptoms such as nausea, light sensitivity and blurred vision, a migraine is conventionally treated through oral medication, either to curb the severity of symptoms during an attack or to prevent future migraine attacks

One treatment protocol achieved a 98% total effective rate and the other acupuncture protocol achieved a 90.7% total effective rate