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Dans tous les cas, il existe des corrlations bien tablies, avec un bon niveau de preuve (relation potentiellement causale), et quelle soit un facteur direct ou indirect, son lvation est un signal dalerte ne pas ngliger

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Reactions which may occur because of this solution, added drugs or the technique of reconstitution or administration include febrile response, local tenderness, abscess, tissue necrosis or infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection and extravasation