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Its involvement in tissue development, particularly in the retina and brain, has been extensively documented (Jabari et al., 2022

Abstract Glyoxalase pathway, comprising glyoxalase I (GLY I) and glyoxalase II (GLY II) enzymes, is the major pathway for detoxification of methylglyoxal (MG) into D-lactate involving reduced glutathione (GSH)

Accuracy limit of rigid 3-point water models

In smoke-induced pulmonary fibrosis models, tranilast treatment significantly reduced inflammatory cytokines (IL-1, TNF-, TGF-1), oxidative stress, and NF-B expression, while also inhibiting fibroblast proliferation in lung tissue [150]