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Growth hormone/IGF-1 axis supports bone and cartilage metabolism (established endocrinology)

Taken together, these observations suggest that except in vitamin B 12 deficiency (which only responds to cyanocobalamin treatment because of the inactivation of methionine synthase), folate treatment should be the most adequate therapy to reverse hyperhomocysteinemia detected both under basal conditions and after an oral methionine load

Stimulation of natural killer and antibody-dependent cellular cytotoxicity activities in mouse leukocytes by bombesin, gastrin-releasing peptide and neuromedin C: involvement of cyclic AMP, inositol 1,4,5-trisphosphate and protein kinase C

B12 isa complex vitamin that is most often found naturally in foods like meat, eggs, dairy, and some fortified foods, so it can sometimes be difficult to achieve high enough levels of B12 if you do not regularly eat these foods