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The involvement of P-glycoprotein in AFB 1 transport is supported by the fact that aflatoxin has been shown to induce mRNA encoding this protein in mouse liver

110 Quercetin, another common flavonoid compound, was found in in vitro experiments to inhibit abnormal PASMC proliferation and induce PASMC apoptosis by blocking the tyrosine receptor kinase A/AKT signaling pathway

Strand separation assay The strand separation assay (10 L volume) was carried out in 25 mM HEPES pH 7.5, 60 mM NaCl, 0.1 g/L BSA, 1 mM MgCl 2 , 1 mM ATP, 10 mM creatine phosphatase, 15 g/ml creatine kinase, and 5 nM fluorescently labelled D-loop substrate (prepared as described previously 32 )