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The mitochondrial permeability transition pore may comprise VDAC molecules

BPC 157 induced the vasorelaxation via eNOS/nitric oxide singling activation In order to investigate whether BPC 157 induced vasorelaxation via eNOS-nitric oxide singling activation, L-NAME (eNOS inhibitor) and hemoglobin (nitric oxide scavenger) were used in further studies

Consistently, anaphase bridges and micronucleation induced by HRASV12 or cyclin E1 overexpression were suppressed by RNase H1 overexpression in U2OS T-REx [RNH1-GFP] cells (Fig