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Epigenetic regulation of RBC-related genes is fundamental for normal development and maintenance of RBCs (Hewitt, Sanalkumar, Johnson, Keles, & Bresnick, 2014)

Nuclear cytoplasmic shuttling by thyroid hormone receptors

Also, in the late phase of M1 macrophage polarization, lactate-derived lactylation of histone lysine residues as observed in conditions of hypoxia and bacterial challenges served as an epigenetic modification that directly stimulated the expression of homeostatic genes that have been traditionally associated with M2-like macrophages (Zhang et al., 2019)

In a subsequent exploratory analysis of the pivotal Phase III trial, among patients receiving CPX-351 consolidation, CPX-351 was administered entirely as outpatient in 51% of the cases during the first consolidation cycle, and in 61% during the second cycle