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For some systems, this sudden shift in gut signaling could be interpreted by the brain's chemoreceptor trigger zone (the area that controls nausea and vomiting) as a sign of trouble, leading to a nauseous sensation

This apparent discrepancy in the release of glycerol and FFA from adipose cells of HSL null mice has been clarified by the observation that diacylglycerol content increased markedly in adipose tissue of HSL null mice [5]