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While the structural insights are unavailable, these observations denote highly specific substrate binding in the VhaA active site

Boca Raton, FL, USA: 2011

Interestingly, of the 10 GSTP-positive cells in 13 cells used here, 8 cell lines (all except for COLO320HSR and HT1080) were proto-oncogene KRAS-mutated cancers that promote carcinogenesis and the aberrant proliferation of cancer cells