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Rac1-activated NOX1 produces ROS, which have been implicated in the process of lung and skin tumorigenesis (Myant et al

Effect of Anti-retroviral Therapy on Glutathione and Cysteine BAL levels GSH and Cys levels were also evaluated among only HIV-infected subjects on and off ART

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This process is characterized by the release of large quantities of neurotransmitters following depolarization, which can intensify neurotransmitter-induced excitotoxicity through activation of NMDA and -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, leading to excessive neuronal excitation and eventual cell death (10, 31)