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Therapeutic strategies targeting mitochondrial dysfunction for comorbidity intervention (Table 2) Enhancing mitochondrial energy metabolism Mitochondrial protectants Coenzyme Q10, a well-established clinical therapeutic agent, is a component of the ETC and plays a dual role in facilitating electron transfer and exerting potent antioxidant effects

Neutrophil autophagy induced by monosodium urate crystals facilitates neutrophil extracellular traps formation and inflammation remission in gouty arthritis

CONSISTENCY IS THE KEY

Research indicates that a robust gut microbiome can enhance the elimination of arsenic through feces and reduce its accumulation in body tissues, such as the liver, kidneys, and brain