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To directly probe the metabolic impact of GOT1/2 deletion in vivo, we employed MALDI imaging to visualize aspartate levels and the lactate/pyruvate ratio as an inverse proxy for cyto-solic NAD + /NADH

Sigma-Tau Pharmaceuticals, Inc

Anyone Pursuing a Healthy Lifestyle L-Carnitine's benefits extend beyond fitness, supporting overall health and well-being

To date, eight different variants, including three frameshift mutations (37.5%), two missense mutations (25.0%), one nonsense mutation (12.5%), one copy number mutation (12.5%), and one six-base in-frame deletion (12.5%), have been reported in China in 10 patients from nine unrelated families (Table 1)