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Furthermore, we investigated whether VRK2 affects the transport of SLC7A11 by regulating ER-to-Golgi or Golgi-to-PM processes

They found that the risk of dementia, particularly vascular dementia or mixed dementia, may increase with high UA levels

The Nrf2 (nuclear factor erythroid 2-related factor 2)Keap1 (Kelch-like ECH-associated protein 1)ARE (antioxidant response element) signaling pathway is a master regulator of cellular defense against oxidative and electrophilic stress