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HSP70 proteins are necessary for cell repair and survival under stressful conditions, their amount correlates with the severity of various pathological conditions, such as ischemia, inflammation, autoimmune processes, malignant tumors, bacterial and viral infections, and neurodegenerative diseases (Ortan et al., 2018

For the initial hit validation screen, primary hits were manually picked from the original compound library, while secondary screening assays were performed with compounds that were re-ordered directly from ChemBridge

Rosa Canina , or RC The oil content and composition of RR and RC is similar, but there are some differences: RR contains 8% of oil, while RC contains a bit more, 10%