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(Esteghamati et al., 2014) documented a significantly relationship among elevated Hcy levels and major manifestations of MetS, including impaired glucose tolerance (IGT), abdominal obesity, elevated blood pressure, and hypertriglyceridemia

Drinking alcohol: drinking can also affect the bodys capacity to absorb B12, which can lead to a deficiency for gastric bypass surgery patients

Oral administration faces hepatic first-pass metabolism, reducing bioavailability to approximately 4050% of subcutaneous routes, but offers convenience for longer-term studies where daily injections create compliance challenges