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[64] demonstrated that dietary supplementation with melatonin or L-tryptophan in Atlantic salmon ( Salmo salar ) effectively mitigated stress-induced cortisol elevation, enhanced antioxidant defences, and improved osmoregulatory function following acute handling stress, suggesting that such functional additives can significantly boost stress resilience in farmed fish

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In our study, blood glucose and insulin resistance started to increase with niacin doses over 500 mg/day