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Preclinical studies also suggest potential roles in pain modulation, immune regulation, and neuroprotection, making it a versatile compound in the field of neurobiology research Supplied as a lyophilized powder in vials (5 mg)

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History [edit] Descriptions of deficiency effects [edit] Between 1849 and 1887, Thomas Addison described a case of pernicious anemia, William Osler and William Gardner first described a case of neuropathy, Hayem described large red cells in the peripheral blood in this condition, which he called "giant blood corpuscles" (now called macrocytes), Paul Ehrlich identified megaloblasts in the bone marrow, and Ludwig Lichtheim described a case of myelopathy