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Description

Mller J, Jrgensen JO, Mller N, et al

This is a reversible modification and adding sodium borohydride (NaBH4) results in the GSH release, which can subsequently react with DTNB and be measured

In some embodiments, about or less than about 75%, 50%, 40%, 30%, 25%, 20%, 15%, 10%, 5%, 1%, or fewer of the nucleotides of the nucleic acid-targeting guide RNA participate in self complementary base pairing when optimally folded

Specific aspects of tandem repeat sequences have been found to be responsible for more than twenty human diseases (New insights into repeat instability: role of RNADNA hybrids