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Parkinsons disease is a neurodegenerative disorder that affects millions of people worldwide

Bibcode:2006Natur.444..744F

Additionally, it modulates inflammasome activation, such as suppressing NLRP3 inflammasome assembly, to reduce inflammatory cytokine release and alleviate hepatic inflammation

ROS may alter the permeability of the mitochondrial membrane and transition potential, resulting into release of proapoptotic factors ( e.g., cytochrome C and caspase-3) and reduced production of ATP