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, d-amino acid substitution, N -methylation, and peptoid incorporation) to side-chain analog replacement and peptide cyclizationhave been developed to enhance proteolytic stability, improve binding affinity, and optimize membrane permeability

Alternative procedures that can assist in the diagnosis of malabsorption from classic pernicious anemia arising from an autoimmune disease or from long-term atrophy or atrophic gastritis, include a combination of anti-intrinsic factor antibodies, and gastrin and pepsinogen A and C in serum (Green et al., 2017)

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