dihexa forum EllieMD Dihexa Research Peptide Protocols: Reconstitution

Earnheart JC, Schweizer C, Crestani F, Iwasato T, Itohara S, Mohler H, Luscher B

QTc Prolongation: QT studies with buprenorphine products have demonstrated QT prolongation 15 msec

Tirzepatide Reconstitution Math Tirzepatide - dose per draw at common vial sizes Vial Size 5 mg BAC Water 1.0 mL Concentration 5 mg/mL 2.5 mg 0.50 mL (50 units) 5 mg 1.00 mL (100 units) 10 mg N/A 15 mg N/A Vial Size 10 mg BAC Water 2.0 mL Concentration 5 mg/mL 2.5 mg 0.50 mL (50 units) 5 mg 1.00 mL (100 units) 10 mg 2.00 mL (200 units*) 15 mg 3.00 mL (300 units*) Vial Size 10 mg BAC Water 1.0 mL Concentration 10 mg/mL 2.5 mg 0.25 mL (25 units) 5 mg 0.50 mL (50 units) 10 mg 1.00 mL (100 units) 15 mg 1.50 mL (150 units*) Vial Size 30 mg BAC Water 3.0 mL Concentration 10 mg/mL 2.5 mg 0.25 mL (25 units) 5 mg 0.50 mL (50 units) 10 mg 1.00 mL (100 units) 15 mg 1.50 mL (150 units*) * Volumes above 100 units exceed a standard 1 mL insulin syringe

Indeed, restoring the FMRP-CYFIP1 deficiency via a small chimeric peptide acting on the dysregulation of protein synthesis could be central for the new FXS pharmacological therapy development