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Melatonin Melatonin, a neuro-hormone produced in the pineal gland, may have a role in gallstone disease prevention or treatment due to its anti-inflammatory and free-radical-scavenging properties, as well as its beneficial effect on gallbladder muscle tone (Pozo 2010

In addition to liver-derived serum IGF-1 (endocrine), there is strong evidence that locally expressed IGF-1 (autocrine/paracrine) regulates longitudinal bone growth in the growth plate [87,127132]

Hussain SA, Sulaiman AA, Alhaddad H, Alhadidi Q

Skin, Hair, and Nails While the "hard" benefits like joint health and recovery get the most attention, the "beauty" benefits of MSM and Vitamin C are a significant perk