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Mota et al

Oral supplementation rarely elevates plasma vitamin C levels above 70 M, whereas IVC at 312 g/day can achieve pharmacologic concentrations up to 110 mM, offering pronounced anti-inflammatory and endothelial-stabilizing effects in critically ill or cardiovascular patients

Dioscin, a natural steroidal saponin metabolite found in various herbs, including Dioscorea bulbifera L

P-coumaric acid is negatively correlated with liver injury parameters in patients with cholestatic liver disease, directly binds NADPH oxidase 2, and inhibits reactive oxygen species production in hepatocytes, thereby preventing hepatocyte death and liver injury