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Toxicol Sci 143(2):268276 Kumar BS, Chung BC, Kwon OS, Jung BH (2012) Discovery of common urinary biomarkers for hepatotoxicity induced by carbon tetrachloride, acetaminophen and methotrexate by mass spectrometry-based metabolomics

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This slowing down can lead to increased absorption of nutrients, which is beneficial for blood sugar control, but may also result in the unwanted side effect of constipation