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Similarly, treatment of 7 with NaBH 4 resulted in the ring-opening and reduced mono-adducts 18 , which was stable and not active toward BME anymore (Fig

In conclusion, histones are not merely structural proteins but are dynamic regulators of genomic function

Results demonstrated that LMWF treatment in bleomycin-induced pulmonary fibrosis mice decreased TGF-, TNF-, and IL-6 expression in lung tissue, mirroring the effects of nintedanib in reducing inflammatory cytokine accumulation