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While these interventions are usually adjuncts to behavioral and educational therapies, understanding their roles, safety, and scientific basis can empower caregivers and clinicians to make informed decisions

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However, the current understanding of nephron segmental metabolism is mainly based on studies that measured specific substrate utilization, ATP production, and abundance or activities of a small number of metabolic enzymes in nephron segments isolated from rats, mice, and other animal models 17,18,19,23

TAC was expressed as the gallic acid equivalent antioxidant capacity (GEAC)