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In exploratory analyses, reductions in TG, RC and LDL-C in participants treated with 6 or 12 mg of TLC-2716 were greatest in participants with higher baseline values of these parameters (Extended Data Fig

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Kinetics of reaction of peroxynitrite with selenium- and sulfur-containing compounds: Absolute rate constants and assessment of biological significance

This therefore implies that CBS oligomerisation could be an evolutionary strategy overall but could involve different structural components and serve different functional outcomes