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Additionally, cellular autophagy is vital in pulmonary diseases as evidenced by the observation that selenium inhibits intracellular Mycobacterium tuberculosis (MTB) by modulating macrophage autophagy-related pathways ( 3 Nanomaterials in inflammation and the mechanical microenvironment Nanomaterials show significant promise in modulating inflammatory responses and influencing the pulmonary mechanical microenvironment, offering novel strategies for respiratory disease treatment

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Damage to mitochondrial DNA results in loss of mitochondrial membrane potential, impairment in the electron transport chain, and drives the immune and inflammatory responses (Liu and Chen, 2017), (Figure 3)

Nature 568 , 566570 (2019)