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384 High salt load may induce persistent hepatic steatosis and inflammation by inhibiting SIRT3 expression, thereby contributing to cardiovascular damage

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[13] In combination with a reduced-calorie diet and increased physical activity, semaglutide (as Wegovy) is indicated to reduce the risk of major adverse cardiovascular events (cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke) in adults with established cardiovascular disease and who are either obese or overweight