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doi: 10.1038/ng.694 42 LiXLWuCFWuGS

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Physiologically, at the cellular level, Mg 2+ is involved in metabolic pathways acting as an enzyme cofactor, contributes to the regulation of membrane stability, regulates ion channels, and acts as an intracellular signal [200, 201]

This study provided additional information on the potential effect of ALCAR on disease progression and survival and adds evidence to justify the use of ALCAR in ALS subjects