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3 Pharmacological treatments 3.1 Corticosteroids Glucocorticoids play a crucial role in the growth and development, while corticosteroids, as synthetic counterparts of glucocorticoids, exhibit properties of anti-inflammatory and immunosuppressive ( 3.1.1 Triamcinolone acetonide Triamcinolone acetonide, a versatile and widely utilized medication belonging to the class of corticosteroids, is available in a diverse range of pharmaceutical forms to cater to different medical needs and modes of application, including ointments, gels, mouthwashes, sprays, and pastes, which is most frequently medication employed for the treatment of mucosal lesions ( Triamcinolone acetonide can reduce the expression of IL-9 in the lesions, leading to the decline of MMP9, to relieve the symptoms of OLP ( Specific patient populations, particularly those grappling with persistent or intricate medical conditions, might require the continuation of this medication's use over an extended period

217 Similarly, PS2 overexpression increases p53 levels and activity to promote p53-dependent cell death, which indicates that APP and its proteolytic products play important roles in the regulation of p53 levels and activity

J Steroid Biochem Mol Biol 2016;155:104-11

Although there are many studies on caffeine and EGCG, there are few multilevel horizontal comparisons between the two drugs, as treatments