McKenna: glutamate as energy substrate and neurotransmitterfunctional interaction between neurons and astrocytes
Curr Opin Struct Biol 18(1):106111 Netz DJ, Stith CM, Stumpfig M, Kopf G, Vogel D, Genau HM, Stodola JL, Lill R, Burgers PM, Pierik AJ (2012) Eukaryotic DNA polymerases require an iron-sulfur cluster for the formation of active complexes
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Epithalon and Geroprotective Outcomes A large, long-term study followed 266 elderly subjects (60+ years) over a 68 year period.(13,14) Participants were divided into groups receiving: Thymalin Epithalon A combination of Thymalin + Epithalon Control conditions Reported outcomes: Improved function of cardiovascular, endocrine, immune, and nervous systems Normalization of metabolic and hemostatic parameters Approximately 2 reduction in the incidence of common age-related diseases (e.g., acute respiratory illnesses, heart disease, and bone pathology) Decreased mortality: ~ 2-fold reduction with Thymalin ~ 1.8-fold reduction with Epithalon ~ 2.5-fold reduction with the combination These data suggest that Epithalon, alone or in combination with other peptide bioregulators, may exhibit geroprotective potential in elderly cohorts under specific experimental conditions