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Several situations warrant pausing at a dose level for additional weeks before escalating: Persistent nausea: If nausea lasts beyond 2 weeks at any dose level, stay at that dose for an additional 2 to 4 weeks

(1989) Role of glutathione peroxidase in the radiation response of mouse kidney, Int

Moreover, the transient burst of oxidative injury after events like myocardial infarction limits the period during which ferroptosis inhibitors are effective

Mol Neurobiol 54:36523664 Xifro X, Vidal-Sancho L, Boadas-Vaello P, Turrado C, Alberch J, Puig T, Verdu E (2015) Novel epigallocatechin-3-gallate (EGCG) derivative as a new therapeutic strategy for reducing neuropathic pain after chronic constriction nerve injury in mice