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Both conditions may require corticosteroids for acute flares, immunomodulators (azathioprine, 6-mercaptopurine), and biologic therapies (anti-TNF agents, vedolizumab, ustekinumab) for moderate to severe disease

It means physician supervision, appropriate patient selection, and honest conversations about what the evidence does and doesn't support

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Reactive oxygen species mediate liver injury through parenchymal NF-B inactivation in prolonged ischemia/reperfusion