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The absence of immunoglobulin A in F11r(+/+)Igha(/) mice did not affect disease, whereas F11r(/)Igha(/) mice displayed markedly increased susceptibility to acute, injury-induced colitis

Previously, without any effective treatment, patients with primary progressive MS faced paralysis and mental decline

For many, chronic body aches and fatigue can lead to emotional distress, affecting mood and overall quality of life

Following injury, CGRP interacts with its receptors CGRP receptor (CRLR) and receptor modifying protein (RAMP-1), which are expressed on Schwann cells, thereby activating the downstream PI3K-Akt pathway and the RAS-Erk1/2 pathway to promote cell proliferation and dedifferentiation essential for peripheral nerve regeneration [111]